Treatment · International
JAMA Psychiatry: psilocybin for treatment-resistant depression: the EPISODE randomized trial
A multi-site randomized trial of psilocybin for adults with treatment-resistant major depression.
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The EPISODE randomized clinical trial published in JAMA Psychiatry reports on the efficacy and safety of psilocybin in adults with treatment-resistant major depression, an addition to a small but growing body of pivotal psychedelic data.
The paper sits in the middle of the post-MDMA-rejection psychedelic regulatory landscape, where trial design and blinding remain the dominant open questions.
Read the full JAMA Psychiatry article for the methodology and outcomes.
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